seroprevalence of anti-hepatitis a antibody among 1 - 15 year old children in kashan-iran

conclusions in this city, a great proportion of children are susceptible to hepatitis a and it’s complications at an older age. this decrease in seropositivity may be caused by elevated hygien level. according to our results hepatitis a vaccination is recommended at early childhood such as that of other regions where low prevalence of hepatitis a infection is found. patients and methods this cross-sectional study was performed on 666 one to fifteen year-old children from health-care centers in kashan city during 2012. total antibodies against hepatitis a were measured in sera by enzyme-linked immunosorbent assay (elisa). results totally, 3.9% of children were seropositive. mean number of family members was 3.92 ± 0.89. there was no difference in seroprevalence of hepatitis a relative to sex, family size, mean age and age groups. objectives this study was performed to determine the seroprevalence of hepatitis a in 1 - 15 year-old children of kashan. background worldwide, hepatitis a is a common infection during childhood especially in developing countries. it can cause severe complications in adults and patients with underlying diseases.